POTENTIAL DRUG INTERACTIONS IN PARTICIPANTS OF A HEALTH EDUCATION PROGRAM, PRESENTING TYPE 2 DIABETIC

Abstract

Cross-sectional study in order to determine the prevalence, clinical impact and factors associated with Potential Drug
Interactions (PDI) in participants with type 2 diabetes (DM2) of a health education program. This study involved 71
diabetics grouped according to the presence or absence of PDI and data were obtained individually by a semi-structured
questionnaire. PDI were classified using the UpToDate® database and the participants were compared according to
socio-demographic and clinical variables through chi-square and t student tests. Each participant used 4.6 drugs
on average and over 70% of participants showed some PDI (total of 140 interactions). Over 70% of them required
monitoring of pharmacotherapy and 6.4% of them would need to consider a change in therapy. PDI increased with
the number of drugs prescribed (p<0.001) and did not change according to the gender, age and duration of DM2