DRUG-FOOD INTERACTIONS AND THEIR INFLUENCE IN PHARMACOTHERAPY

Abstract

The occurrence of interactions between drugs and foods can be decisive events for achieving therapeutic success due to interferences in drug performance and also in nutrient uptake. The objective of this review was to highlight drugfood interactions with impact on health, and discuss about the appropriate measures to avoid or minimize them. Several authors point that the most important food-drug interactions are those that affect drug bioavailability. Fortunatelly, many of the interaction mechanisms have been elucidated. Therefore, food-drug interaction studies are important contributions to ensure the correct use of drugs and enable the development of suitable clinical protocols.