EXCIPIENTS FOR DIRECT COMPRESSION TABLET PRODUCTION

Tiago Rafael Sausen, Paulo Mayorga

Abstract


The pharmaceutical industry’s interest in the tablet production by direct compression has increased in recent years, especially because it is an easy to control and less process time production method, leading to greater productivity of the production line. However, the successful production of tablets by direct compression relies almost exclusively of
adjuvants that comprise the formulation. This article describes the production of tablets by direct compression, addressing the characteristics and key excipients involved in this process.

Keywords


excipients; pharmaceutical technology; tablets



DOI: http://dx.doi.org/10.14450/2318-9312.v25.e4.a2013.pp199-205

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Infarma - Ciências Farmacêuticas

ISSN - 2318-9312 (Versão eletrônica)

ISSN - 0104-0219 (Versão impressa)

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Diretoria

Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia

Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia

João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia

Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia