BENEFITS OF RESVERATROL AS AN ACTIVE COMPONENT IN THE PREVENTION OF SKIN AGING

Andreia Medeiros Paladini, Talita Durante Lopes, Karina Elisa Machado

Abstract


The improvement of the health parameters of the population is one of the most outstanding achievements of humankind, and this achievement has become a challenge for today. Living more is important as long as we can add quality of life, physical and mental, for the years we have won, and therefore the search for resources that can help us achieve this goal has stimulated new research and among these, of active ingredients to be used in cosmetic formulations that can combat skin aging. The aging of the skin may be intrinsic, meaning, arising from the natural passage of time and genetics of the body. Or it may be extrinsic, due to environmental factors interacting with the skin and many of these factors are related to the production of free radicals, such as smoking, excessive consumption of alcohol and stress, in this context, one of the assets that draw our attention in combating skin aging is resveratrol. Resveratrol is a phenolic compound found in various plants and foods, such as peanut, grape, and its derivatives. This compound carries a variety of biological activities such as antioxidants, anti-inflammatory, cardioprotective, chemopreventive, and neuroprotective. The present article is characterized as being a descriptive bibliographical research with a qualitative approach and aims to carry out an updated bibliographic review on resveratrol and its use in the prevention of cutaneous aging. It is concluded that resveratrol has an antioxidant action and is an activator of sirtuin 1, which in turn activates DNA repair proteins, which may be useful in anti-aging treatment.


Keywords


skin aging, free radicals, rejuvenation, resveratrol, sirtuin 1



DOI: http://dx.doi.org/10.14450/2318-9312.v32.e4.a2020.pp319-328

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Copyright (c) 2020 Andreia Medeiros Paladini, Talita Durante Lopes, Karina Elisa Machado

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Infarma - Ciências Farmacêuticas

ISSN - 2318-9312 (Versão eletrônica)

ISSN - 0104-0219 (Versão impressa)

Conselho Federal de Farmácia - CFF

SHIS QI 15 Lote "L" - Lago Sul - Brasília - DF

CEP: 71635-615 - Fone: (61)3878-8751

e-mail:infarma@cff.org.br

Diretoria

Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia

Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia

João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia

Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia