PHARMACOKINETICS AND TERATOGENICITY MECHANISMS OF MEDICINES IN PREGNANCY: A REVIEW

Andréia Moreira Andrade, Alanderson Alves Ramalho, Simone Perufo Opitz, Fernanda Andrade Martins, Rosalina Jorge Koifman

Abstract


The presence of emerging contaminants in surface Physiological changes that occur during a gestational period on a female organism are greatly explored by researchers and it is well elucidated by scientific literature, however, the
theme: pharmacokinetics and mechanisms of teratogenicity by medicines on female organisms passing by physiological changes, it is still poorly explored. The research’s purpose was to review and contribute to adding scientific knowledge
about pharmacokinetics and mechanisms of teratogenicity by drugs used during gestation.


Keywords


Pharmacokinetics; Abnormalities, Drug-Induced; Pregnancy



DOI: http://dx.doi.org/10.14450/2318-9312.v29.e2.a2017.pp100-107

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Copyright (c) 2017 Andréia Moreira Andrade, Alanderson Alves Ramalho, Simone Perufo Opitz, Fernanda Andrade Martins, Rosalina Jorge Koifman

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Infarma - Ciências Farmacêuticas

ISSN - 2318-9312 (Versão eletrônica)

ISSN - 0104-0219 (Versão impressa)

Conselho Federal de Farmácia - CFF

SHIS QI 15 Lote "L" - Lago Sul - Brasília - DF

CEP: 71635-615 - Fone: (61)3878-8751

e-mail:infarma@cff.org.br

Diretoria

Walter da Silva Jorge João, Presidente do Conselho Federal de Farmácia

Lenira da Silva Costa, Vice-Presidente do Conselho Federal de Farmácia

João Samuel de Morais Meira, Tesoureiro do Conselho Federal de Farmácia

Luiz Gustavo de Freitas Pires, Secretário-Geral do Conselho Federal de Farmácia